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引用本文:   南琼, 唐景春, 何若竹, 胡羽成, 吴涛. 超高效液相色谱-质谱联用检测土壤中两种抗生素呋喃唑酮和氟苯尼考. 分析化学, 2017, 45(11): 1600-1605. doi:  10.11895/j.issn.0253-3820.160870 [复制]

Citation:   NAN Qiong, TANG Jing-Chun, HE Ruo-Zhu, HU Yu-Cheng, WU Tao. Determination of Furazolidone and Florfenicol in Soil by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry. Chinese Journal of Analytical Chemistry, 2017, 45(11): 1600-1605. doi: 10.11895/j.issn.0253-3820.160870 [复制]

超高效液相色谱-质谱联用检测土壤中两种抗生素呋喃唑酮和氟苯尼考

通讯作者:  唐景春, tangjch@nankai.edu.cn

收稿日期: 2016-11-28

接受日期: 2017-09-04

出版日期: 2017-11-20

基金项目: 本文系水体污染控制与治理科技重大专项(No.2015ZX07203-011-06)、天津市水务局局科研项目(No.KY2015-01)和863成果转化项目(No.14RCHZSF00144)资助

Determination of Furazolidone and Florfenicol in Soil by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry

Corresponding author:  TANG Jing-Chun, tangjch@nankai.edu.cn

Received Date:  2016-11-28

Accepted Date:  2017-09-04

Published Date:  2017-11-20

建立了超高效液相色谱-串联质谱(UPLC/MS/MS)检测土壤中多种环境基质下呋喃唑酮和氟苯尼考的方法。提取液采用磷酸盐缓冲溶液(pH=3)-乙腈(3:7,V/V),经过SPE固相萃取小柱SAX-HLB串联富集,使用Waters BEH C18色谱柱(2.1×100 mm)进行分离,UPLC/MS/MS在多反应监测模式下进行定性与定量分析。以3倍信噪比确定方法检出限,以10倍信噪比确定方法定量限。结果表明,本方法在5 min内即可分离两种物质,呋喃唑酮和氟苯尼考的检出限分别为1.19和0.41μg/kg;定量限分别为3.40和1.37μg/kg。50μg/L加标水平的呋喃唑酮和氟苯尼考的回收率分别为92%和79%;200μg/L加标水平下呋喃唑酮与氟苯尼考的回收率分别为96%和86%。

关键词:   超高效液相色谱-串联质谱, 呋喃唑酮, 氟苯尼考, 固相萃取
Key words:   Ultra performance liquid chromatography-tandem spectrometry, Furazolidone, Florfenicol, Solid phase extraction
[1]

Cooper K M, Elliott C T, Kennedyz D G. J. Food Addit. Contam., 2004, 9(21): 841-848

[2]

Sai N, Chen Y P, Liu N, Yu G G, Su P, Feng Y, Zhou Z J, Liu X Y, Zhou HY, Gao Z X, Ning B A. Talanta, 2010, 82: 1113-1121. doi: 10.1016/j.talanta.2010.06.018

[3]

Holt P, Harvey D, Hurley R. Adverse Drug React. Toxicol. Rev., 1993, 12(2): 83-89

[4]

Saba A B, Ola-Davies O, Oyeyemi M O, Ajala O. J. Afr. J. Biomed. Res., 2000, 3: 133-137

[5]

Wang J, Macneil J D, Kay J F. J. John Wiley & Sons Inc, Hoboken, NJ, USA, 2011, : 121-123

[6]

BangemannM.Cominission Regulation (EC) No 1430/94, Official Journal of the European Cominunities, Brussels, Belgium (1994)

[7]

Ryan J J, Lee Y C, Dupont J A, Charbonneau C F. J. Assoc. Official Anal. Chem., 1975, 58: 1227-1238

[8]

Official Methods of Analysis of the Association of Official Analytical Chemists. AOAC Inc., 14th ed., 1984

[9]

Botsoglou N A. J. Agr. Food Chem., 1988, 36(6): 1224-1227. doi: 10.1021/jf00084a024

[10]

Schering-Plough Animal Health Corporation.Aquafen, AquaflorFlorocol.J. Technical Monograph. New Jersey, USA.http://www.spaquaculture.com/assets/aquaflor, 2003

[11]

NY 5071-2002, The Pollution-free Food Fish with Drug Use. The Ministry of Agriculture of the People's Republic of China. 2002

中华人民共和国农业部. 无公害食品渔用药物使用准则NY 5071-2002, 2002

[12]

Saari L, Peltonen K. J. Food Addit. Contam. A, 2004, 21(9): 825-832. doi: 10.1080/02652030400002329

[13]

Kaniou I, Zachariadis G, Kalligas G, Tsoukali H, Stratis J. J. Liq. Chromatogr., 1994, 17: 1385-. doi: 10.1080/10826079408013771

[14]

Wilhelmus, Be, Marinus, Aerts. J. Nucl. Med. Biol., 2017, 44: 90-104. doi: 10.1016/j.nucmedbio.2016.10.002

[15]

Fernando R, Munasinghe D M S, Gunasena A R C, Abeynayake P. J. Food Control, 2017, 72: 300-305. doi: 10.1016/j.foodcont.2015.08.044

[16]

Cornejo J, Pokrant E, Riquelme R, Briceno C, Maddaleno A, Araya-Jordan C, San M. Food Addit. Contam., 2017, 34(4): 469-476. doi: 10.1080/19440049.2016.1267876

[17]

Lee Y J, Choi J H, Abd El-Aty A M, Chung H S, Lee H S, Kim S W, Rahman M M, Park B J, Kim J E, Shin H C. J. Sep. Sci., 2017, 40(2): 415-423. doi: 10.1002/jssc.v40.2

[18]

Orlando E A, Costa R, Aline G, Losekann , Marcos E. J. Chromatogr. B, 2016, 1035: 8-15. doi: 10.1016/j.jchromb.2016.09.013

[19]

XIE Kai-Zhou, XU Dong, CHEN Shu-Qin, XIE Xing, JIA Long-Fei, HUANG Yu-Ping, GUO Hui-Sheng, WANG Jin-Yu, LIU Zong-Ping. Chinese J. Anal. lab., 2011, 30(7): 31-35

谢恺舟, 徐东, 陈书琴, 谢星, 贾龙飞, 黄玉萍, 郭辉生, 王金玉, 刘宗平. 分析试验室, 2011, 30(7): 31-35

[20]

GUO Xia, ZHANG Su-Xia, SHEN Zhong-Jian, LI Jian-Cheng. Chinese J. CVS., 2006, 36(9): 743-747

郭霞, 张素霞, 沈建忠, 李建成. 中国兽医科学, 2006, 36(9): 743-747

[21]

Pfenning A P, Roybal J E, Rupp H S. J. AOAC Inter., 1998, 81(4): 714-

[22]

Tong L, Li P, Wang Y X, Zhu K Z. Chemosphere, 2009, 74(8): 1090-1097. doi: 10.1016/j.chemosphere.2008.10.051

[23]

DIAO Shi-Qiang, WU Yan-Yan, LI Lai-Hao, YANG Xian-Qing, SHAO Zheng-Yi, SUN Man-Yi, CHEN Xiao-Feng. Chinese J.Scfs., 2010, 6(2): 53-58

刁石强, 吴燕燕, 李来好, 杨贤庆, 邵征翌, 孙满义, 陈晓凤. 南方水产, 2010, 6(2): 53-58

[24]

LI Xiao-Jing, HUANG Cong, YU Hong, Zhu Hui-Yang, GAN Ping-Sheng. Chinese J. Env. Health, 2013, 30(5): 437-439

李晓晶, 黄聪, 于鸿, 朱惠杨, 甘平胜. 环境与健康杂志, 2013, 30(5): 437-439

[25]

MA Li-Li, GUO Chang-Sheng, HU Wei, SHA Jian, ZHU Xing-Wang, RUAN Yue-Pei, WANG Yu-Qiu. Chinese J. Anal. Chem., 2010, 38(1): 21-26

马丽丽, 郭昌胜, 胡伟, 沙健, 朱兴旺, 阮悦斐, 王玉秋. 分析化学, 2010, 38(1): 21-26

[26]

LI Ling-Ling, HUANG Li-Dong, HUO Jia-Heng, ZHONG Ren-Ci, ZHANG Yong-Song. Chinese J.PNF., 2010, 16(5): 1176-1182. doi: 10.11674/zwyf.2010.0535

李玲玲, 黄利东, 霍嘉恒, 钟仁赐, 章永松. 植物营养与肥料学报, 2010, 16(5): 1176-1182. doi: 10.11674/zwyf.2010.0535

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超高效液相色谱-质谱联用检测土壤中两种抗生素呋喃唑酮和氟苯尼考

南琼, 唐景春, 何若竹, 胡羽成, 吴涛

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