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引用本文:   张朝辉, 陈应庄, 陈波, 马铭. 直喷离子化质谱法快速鉴别粉防己和广防己. 分析化学, 2020, 48(9): 1236-1243. doi:  10.19756/j.issn.0253-3820.191725 [复制]

Citation:   ZHANG Zhao-Hui , CHEN Ying-Zhuang , CHEN Bo , MA Ming . Rapid Differentiation of Stephania tetrandra and Aristolochia fangchi by Direct Spray Mass Spectrometry. Chinese Journal of Analytical Chemistry, 2020, 48(9): 1236-1243. doi: 10.19756/j.issn.0253-3820.191725 [复制]

直喷离子化质谱法快速鉴别粉防己和广防己

通讯作者:  马铭, mingma@hunnu.edu.cn

收稿日期: 2019-12-08

基金项目: 本文系国家自然科学基金项目(Nos.21775041,21775040)资助

Rapid Differentiation of Stephania tetrandra and Aristolochia fangchi by Direct Spray Mass Spectrometry

Corresponding author:  MA Ming , mingma@hunnu.edu.cn

Received Date:  2019-12-08

Fund Project:  This work was supported by the National Natural Science Foundation of China (Nos. 21775041, 21775040).

采用直喷离子化质谱法,通过对粉防己中的粉防己碱和防己诺林碱、广防己中的马兜铃酸A和木兰花碱的敞开式质谱行为进行研究,获得了粉防己(Stephania tetrandra)及其有毒伪品广防己(Aristolochia fangchi)的敞开式质谱轮廓,建立了直喷离子化质谱法简单快速鉴别粉防己和广防己的方法。结果表明,在正离子模式下,从敞开式质谱轮廓上,可以利用粉防己的标志性成分粉防己碱和防己诺林碱对粉防已和广防己进行快速鉴别。此方法具有简单、快速、无需样品前处理等优点,对防己药材的质量控制具有重要参考价值。研究了马兜铃酸A在敞开式质谱条件下的电喷雾电离行为,对敞开式质谱检测技术分析马兜铃酸A有借鉴意义。

关键词:   直喷离子化质谱法, 粉防己, 广防己, 防己诺林碱, 粉防己碱, 木兰花碱, 马兜铃酸A
Key words:   Direct spray mass spectrometry, Stephania tetrandra, Aristolochia fangchi, Fangchinoline, Tetrandrine, Magnoflorine, Aristolochic acid A
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直喷离子化质谱法快速鉴别粉防己和广防己

张朝辉, 陈应庄, 陈波, 马铭

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