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引用本文:   白志坤, 张逸涛, 李社红, 罗红霞. 聚L-精氨酸修饰柔性石墨烯平面电极对黄嘌呤的选择性检测. 分析化学, 2020, 48(9): 1149-1159. doi:  10.19756/j.issn.0253-3820.201019 [复制]

Citation:   BAI Zhi-Kun , ZHANG Yi-Tao , LI She-Hong , LUO Hong-Xia . A Flexible Electrochemical Sensor Based on L-Arginine Modified Chemical Vapor Deposition Graphene Platform Electrode for Selective Determination of Xanthine. Chinese Journal of Analytical Chemistry, 2020, 48(9): 1149-1159. doi: 10.19756/j.issn.0253-3820.201019 [复制]

L-精氨酸修饰柔性石墨烯平面电极对黄嘌呤的选择性检测

通讯作者:  罗红霞, luohx@ruc.edu.cn

收稿日期: 2020-01-08

基金项目: 本文系国家自然科学基金项目(No.21575160)资助

A Flexible Electrochemical Sensor Based on L-Arginine Modified Chemical Vapor Deposition Graphene Platform Electrode for Selective Determination of Xanthine

Corresponding author:  LUO Hong-Xia , luohx@ruc.edu.cn

Received Date:  2020-01-08

Fund Project:  This work was supported by the National Natural Science Foundation of China (No. 21575160).

在聚甲基丙烯酸甲酯(PMMA)的辅助下,将化学气相沉积(CVD)得到的石墨烯从铜基底转移到聚对苯二甲酸乙二醇酯(PET)基底上,制备了柔性石墨烯平面电极(GPE)。通过电化学沉积在GPE表面修饰L-精氨酸(L-Arg),得到聚L-Arg修饰的柔性石墨烯平面电极(P(L-Arg)/GPE)。用扫描电子显微镜(SEM)、能谱法(EDS)和拉曼光谱对此电极进行了表征。用循环伏安法(CV)和微分脉冲伏安法(DPV)研究了P(L-Arg)/GPE对黄嘌呤(XA)的电化学传感作用。在尿酸(UA)和次黄嘌呤(HX)存在下,P(L-Arg)/GPE传感器不仅实现了对XA的选择性测定,而且还成功实现了XA、UA和HX的同时测定,3个氧化峰的峰-峰电位差分别为420和384 mV。XA在0.5-8 μmol/L和8-140 μmol/L浓度范围内,响应电流与XA浓度分段呈良好的线性关系,检出限为0.08 μmol/L(S/N=3)。此传感器具有稳定性好、重复性强、响应时间短、制作成本低、抗干扰能力强等优点,并成功应用于人血清中XA测定。

关键词:   石墨烯平面电极, 电化学传感, L-精氨酸, 黄嘌呤, 尿酸, 次黄嘌呤
Key words:   Graphene platform electrode, Electrochemical sensing, L-Arginine, Xanthine, Uric acid, Hypoxanthine
[1]

Zhang X J, Dong J P, Qian X Z, Zhao C J. Sens. Actuators B,2015,221:528-536

[2]

Tang X F, Liu Y, Hou H Q, You T Y. Talanta,2011,83(5):1410-1414

[3]

Yamamoto T, Moriwaki Y, Takahashi S. Clin. Chim. Acta,2005,356(1-2):35-57

[4]

Caussé E, Pradelles A, Dirat B, Negre-Salvayre A, Salvayre R, Couderc F. Electrophoresis,2007,28(3):381-387

[5]

Pagliarussi R S, Freitas L A, Bastos J K. J. Sep. Sci.,2002,25(5-6):371-374

[6]

Cooper N, Khosravan R, Erdmann C, Fiene J, Lee J W. J. Chromatogr. B,2006,837(1-2):1-10

[7]

Amigo J M, Coello J, Maspoch S. Anal. Bioanal. Chem.,2005,382(6):1380-1388

[8]

Hlavay J, Haemmerli S D, Guilbault G G. Biosens. Bioelectron.,1994,9(3):189-195

[9]

Kelley E E, Trostchansky A, Rubbo H, Freeman B A, Radi R, Tarpey M M. J. Biol. Chem.,2004,279(36):37231-37234

[10]

Shan D, Wang Y N, Zhu M J, Xue H G, Cosnier S, Wang C Y. Biosens. Bioelectron.,2009,24(5):1171-1176

[11]

Zhang F Y, Wang Z H, Zhang Y Z, Zheng Z X, Wang C M, Du Y L, Ye W C. Talanta,2012,93:320-325

[12]

Devi R, Yadav S, Pundir C S. Analyst,2012,137(3):754-759

[13]

Pundir C S, Devi R. Enzyme Microb. Technol.,2014,57:55-62

[14]

Devi R, Thakur M, Pundir C S. Biosens. Bioelectron.,2011,26(8):3420-3426

[15]

Novoselov K S, Geim A K, Morozov S V, Jiang D, Zhang Y, Dubonos S V, Grigorieva I V, Firsov A A. Science,2004,306(5696):666-669

[16]

He D Y, Zhang P, Li S H, Luo H X. J. Electroanal. Chem.,2018,823:678-687

[17]

Song Y, Luo Y N, Zhu C Z, Li H, Du D, Lin Y H. Biosens. Bioelectron.,2016,76:195-212

[18]

Kuila T, Bose S, Khanra P, Mishra A K, Kim N H, Lee J H. Biosens. Bioelectron.,2011,26(12):4637-4648

[19]

Emtsev K V, Bostwick A, Horn K, Jobst J, Kellogg G L, Ley L, McChesney J L, Ohta T, Reshanov S A, Röhrl J, Rotenberg E, Schmid A K, Waldmann D, Weber H B, Seyller T. Nat. Mater.,2009,8(3):203-207

[20]

Bunch J S, van Der Zande A M, Verbridge S S, Frank I W, Tanenbaum D M, Parpia J M,Craighead H G, McEuen P L. Science,2007,315(5811):490-493

[21]

Stankovich S, Piner R D, Chen X Q, Wu N Q, Nguyen S T, Ruoff R S. J. Mater. Chem.,2006,16(2):155-158

[22]

He D Y, Li S H, Zhang P, Luo H X. Anal. Methods,2017,9(47):6689-6697

[23]

Novoselov K S, Fal V I, Colombo L, Gellert P R, Schwab M G, Kim K. Nature,2012,490(7419):192-200

[24]

Zhang D D, Li L Z, Ma W N, Chen X, Zhang Y M. Mat. Sci. Eng. C,2017,70:241-249

[25]

Fardet A, Boirie Y. Nutr. Rev.,2013,71(10):643-656

[26]

Li K, Jiang J Y, Dong Z L, Luo H X, Qu L T. Chem. Commun.,2015, 51(42):8765-8768

[27]

Jiang J Y, Zhang P, Liu Y, Luo H X. Anal. Methods,2017,9(14):2205-2210

[28]

Cao Q, Zhao H, Yang Y M, He Y J, Ding N, Wang J, Wu Z J, Xiang K X, Wang G W. Biosens. Bioelectron.,2011,26(8):3469-3474

[29]

Suk J W, Kitt A, Magnuson C W, Hao Y F, Ahmed S, An J, Swan A K, Goldberg B B, Ruoff R S. ACS Nano,2011,5(9):6916-6924

[30]

Kang J M, Shin D, Bae S, Hong B H. Nanoscale,2012,4(18):5527-5537

[31]

Dresselhaus M S, Jorio A, Hofmann M, Dresselhaus G, Saito R. Nano Lett.,2010,10(3):751-758

[32]

Sun Z Z, Yan Z, Yao J, Beitler E, Zhu Y, Tour J M. Nature,2010,468(7323):549-552

[33]

Tavana T, Khalilzadeh M A, Karimi-Maleh H, Ensafi A A, Beitollahi H, Zareyee D. J. Mol. Liq.,2012,168:69-74

[34]

Li S J, Zhang J C, Li J, Yang H Y, Meng J J, Zhang B. Sens. Actuators B,2018,260:1-11

[35]

Laviron E. J. Electroanal. Chem.,1979,101(1):19-28

[36]

Zhu D, Guo D X, Zhang L L, Tan L C, Pang H J, Ma H Y, Zhai M. Sens. Actuators B,2019,281:893-904

[37]

Wen Y P, Chang J, Xu L J, Liao X N, Bai L, Lan Y D, Li M F. J. Electroanal. Chem.,2017,805:159-170

[38]

Vishnu N, Gandhi M, Rajagopal D, Kumar A S. Anal. Methods,2017,9(15):2265-2274

[39]

Zhang L, Li S B, Xin J J, Ma H Y, Pang H J, Tan L C, Wang X M. Microchim. Acta,2019,186(1):9

[40]

Ibrahim H, Temerk Y. Sens. Actuators B,2016,232:125-137

[41]

Wang M, Zheng Z X, Liu J J, Wang C M. Electroanalysis,2017,29(5):1258-1266

[42]

Raj M A, John S A. Anal. Chim. Acta,2013,771:14-20

[43]

Sen S, Sarkar P. RSC Adv.,2015,5(116):95911-95925

[44]

Wang Y, Tong L L. Sens. Actuators B,2010,150(1):43-49

[45]

Luo A, Lian Q W, An Z Z, Li Z, Guo Y Y, Zhang D X, Xue Z H, Zhou X B, Lu X Q . J. Electroanal. Chem.,2015,756:22-29

[46]

Ojani R, Alinezhad A, Abedi Z. Sens. Actuators B,2013,188:621-630

[47]

Ibrahim H, Temerk Y. J. Electroanal. Chem.,2016,780:176-186

[48]

Mu S L, Shi Q F. Biosens. Bioelectron.,2013,47:429-435

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L-精氨酸修饰柔性石墨烯平面电极对黄嘌呤的选择性检测

白志坤, 张逸涛, 李社红, 罗红霞

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