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引用本文:   张琳, 马明英, 李宝强, 孔景临, 张四纯, 张新荣. 纳米金辅助低温等离子体常压质谱快速检测化学毒剂模拟剂. 分析化学, 2020, 48(10): 1416-1421. doi:  10.19756/j.issn.0253-3820.201146 [复制]

Citation:   ZHANG Lin , MA Ming-Ying , LI Bao-Qiang , KONG Jing-Lin , ZHANG Si-Chun , ZHANG Xin-Rong . Rapid Detection of Chemical Warfare Agent Simulants Using Gold Nanoparticles Substrate-assisted Enhanced Low Temperature Plasma-Mass Spectrometry. Chinese Journal of Analytical Chemistry, 2020, 48(10): 1416-1421. doi: 10.19756/j.issn.0253-3820.201146 [复制]

纳米金辅助低温等离子体常压质谱快速检测化学毒剂模拟剂

通讯作者:  张四纯, sczhang@mail.tsinghua.edu.cn

收稿日期: 2020-03-21

Rapid Detection of Chemical Warfare Agent Simulants Using Gold Nanoparticles Substrate-assisted Enhanced Low Temperature Plasma-Mass Spectrometry

Corresponding author:  ZHANG Si-Chun , sczhang@mail.tsinghua.edu.cn

Received Date:  2020-03-21

低温等离子体探针-质谱(LTP-MS)技术可快速检测气、液、固态样品,具有操作简单、快速准确、易小型化等特点,非常适于化学毒剂的现场快速检测。化学毒剂维埃克斯(VX)和芥子气(HD)的毒性强、沸点高、挥发性差,常以气溶胶或液滴态分散于地面、装备或衣服等表面,采用LTP-MS检测存在解吸附难和离子化效率较低的问题。本研究建立了一种纳米金(AuNPs)基底辅助LTP-MS快速检测方法,实现了土壤中VX模拟剂马拉硫磷和HD模拟剂2-氯乙基乙基硫醚(CEES)的快速检测。在氦气出口压力为0.12 MPa、交流电源功率为75 W等优化实验条件下,两种模拟剂的质谱信号强度均比无AuNPs辅助时提高7~9倍。两种模拟剂在5.0~1000 μg/g浓度范围内有良好的线性关系,相关系数(R2)分别为0.9784和0.9915,检出限分别为1.5和1.0 μg/g。本方法通过AuNPs基底与等离子体作用有效提高了难挥发固、液态化合物的离子化效率,具有快速、准确、灵敏的特点,在化学毒剂检测等领域有潜在的应用前景。

关键词:   化学毒剂, 低温等离子体探针, 常压离子源质谱, 纳米金
Key words:   Chemical warfare agents, Low temperature plasma probe, Ambient ionization mass spectrometry, Gold nanoparticles
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纳米金辅助低温等离子体常压质谱快速检测化学毒剂模拟剂

张琳, 马明英, 李宝强, 孔景临, 张四纯, 张新荣

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